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Direct Synthesis of α-Thio Aromatic Acids from Aromatic Amino Acids
Modified amino acids are useful synthetic components in both chemistry and biology. Here we describe a simple, scalable two-step procedure to generate α-thio aromatic acids from aromatic amino acids with yields of up to 96%. Diazotization and α-lactone mediated bromination efficiently form the α-bro...
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| Udgivet i: | Tetrahedron Lett |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6101259/ https://ncbi.nlm.nih.gov/pubmed/30140110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2018.02.030 |
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