Low-dose eribulin mesylate exerts antitumor effects in gastric cancer by inhibiting fibrosis via the suppression of epithelial–mesenchymal transition and acts synergistically with 5-fluorouracil

BACKGROUND: Characterized by aggressive proliferation, extensive stromal fibrosis, and resulting drug resistance, peritoneal dissemination in gastric cancer remains associated with poor prognosis. Interaction between cancer and stromal cells accelerates tumor progression via epithelial–mesenchymal t...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Kurata, Toru, Fushida, Sachio, Kinoshita, Jun, Oyama, Katsunobu, Yamaguchi, Takahisa, Okazaki, Mitsuyoshi, Miyashita, Tomoharu, Tajima, Hidehiro, Ninomiya, Itasu, Ohta, Tetsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101023/
https://ncbi.nlm.nih.gov/pubmed/30147370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S167846
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