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The effect of HIF-1α and PKM1 expression on acquisition of chemoresistance

BACKGROUND: In patients with gastric cancer, one of the greatest obstacles to effective chemotherapy is the development of chemoresistance. It has been previously reported that hypoxia-inducible factor-1 alpha (HIF-1α) is associated with acquisition of chemoresistance, and more recent studies have a...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Okazaki, Mitsuyoshi, Fushida, Sachio, Tsukada, Tomoya, Kinoshita, Jun, Oyama, Katsunobu, Miyashita, Tomoharu, Ninomiya, Itasu, Harada, Shinichi, Ohta, Tetsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037278/
https://ncbi.nlm.nih.gov/pubmed/30013393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S166136
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