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Structure-Dependent Activity of Natural GABA(A) Receptor Modulators

GABA(A) receptors are ligand-gated ion channels consisting of five subunits from eight subfamilies, each assembled in four hydrophobic transmembrane domains. This pentameric structure not only allows different receptor binding sites, but also various types of ligands, such as orthosteric agonists an...

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Bibliografiske detaljer
Udgivet i:Molecules
Hovedforfatter: Çiçek, Serhat Sezai
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100244/
https://ncbi.nlm.nih.gov/pubmed/29932138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23071512
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