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Structure-Dependent Activity of Natural GABA(A) Receptor Modulators

GABA(A) receptors are ligand-gated ion channels consisting of five subunits from eight subfamilies, each assembled in four hydrophobic transmembrane domains. This pentameric structure not only allows different receptor binding sites, but also various types of ligands, such as orthosteric agonists an...

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Detalhes bibliográficos
Publicado no:Molecules
Autor principal: Çiçek, Serhat Sezai
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100244/
https://ncbi.nlm.nih.gov/pubmed/29932138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23071512
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