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Phosphorus Pentachloride Promoted gem-Dichlorination of 2′- and 3′-Deoxynucleosides

Halogen substitution at various positions of canonical nucleosides has generated a number of bioactive structural variants. Herein, the synthesis of two unique series of sugar modified nucleosides bearing a gem-dichloro group is presented. The synthetic plan entails the controlled addition of phosph...

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Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: da Paixao Soares, Fabio, Groaz, Elisabetta, Herdewijn, Piet
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100136/
https://ncbi.nlm.nih.gov/pubmed/29914115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23061457
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