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Computational Insight into the Effect of Natural Compounds on the Destabilization of Preformed Amyloid-β(1–40) Fibrils

One of the principal hallmarks of Alzheimer’s disease (AD) is related to the aggregation of amyloid-β fibrils in an insoluble form in the brain, also known as amyloidosis. Therefore, a prominent therapeutic strategy against AD consists of either blocking the amyloid aggregation and/or destroying the...

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Pubblicato in:Molecules
Autori principali: Tavanti, Francesco, Pedone, Alfonso, Menziani, Maria Cristina
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100107/
https://ncbi.nlm.nih.gov/pubmed/29857500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23061320
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