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The Mechanism for siRNA Transmembrane Assisted by PMAL
The capacity of silencing genes makes small interfering RNA (siRNA) appealing for curing fatal diseases. However, the naked siRNA is vulnerable to and degraded by endogenous enzymes and is too large and too negatively charged to cross cellular membranes. An effective siRNA carrier, PMAL (poly(maleic...
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| Published in: | Molecules |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6099945/ https://ncbi.nlm.nih.gov/pubmed/29966273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23071586 |
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