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[(18)F]FEPPA a TSPO Radioligand: Optimized Radiosynthesis and Evaluation as a PET Radiotracer for Brain Inflammation in a Peripheral LPS-Injected Mouse Model
[(18)F]FEPPA is a specific ligand for the translocator protein of 18 kDa (TSPO) used as a positron emission tomography (PET) biomarker for glial activation and neuroinflammation. [(18)F]FEPPA radiosynthesis was optimized to assess in a mouse model the cerebral inflammation induced by an intraperiton...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6099542/ https://ncbi.nlm.nih.gov/pubmed/29875332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23061375 |
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