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Effects of High‐ and Low‐Fat Meals on the Pharmacokinetics of Ozanimod, a Novel Sphingosine‐1‐Phosphate Receptor Modulator

Ozanimod (RPC1063) is an oral selective modulator of the sphingosine‐1‐phosphate 1 and 5 receptors under development for the treatment of relapsing multiple sclerosis and inflammatory bowel disease. The effects of high‐fat and low‐fat meals on the pharmacokinetics (PK) of a single oral dose of ozani...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Drug Dev
Main Authors: Tran, Jonathan Q., Hartung, Jeffrey P., Tompkins, Cindy‐Ann, Frohna, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099448/
https://ncbi.nlm.nih.gov/pubmed/29125718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.409
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