Pericyte‐derived bone morphogenetic protein 4 underlies white matter damage after chronic hypoperfusion

Subcortical small vessel disease (SVD) is characterized by white matter damage resulting from arteriolosclerosis and chronic hypoperfusion. Transforming growth factor beta 1 (TGFB1) is dysregulated in the hereditary SVD, CARASIL (cerebral autosomal recessive arteriopathy with subcortical infarcts an...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Uemura, Maiko T., Ihara, Masafumi, Maki, Takakuni, Nakagomi, Takayuki, Kaji, Seiji, Uemura, Kengo, Matsuyama, Tomohiro, Kalaria, Raj N., Kinoshita, Ayae, Takahashi, Ryosuke
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099372/
https://ncbi.nlm.nih.gov/pubmed/28470822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12523
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