Melatonin prevents Drp1‐mediated mitochondrial fission in diabetic hearts through SIRT1‐PGC1α pathway

Myocardial contractile dysfunction is associated with an increase in mitochondrial fission in patients with diabetes. However, whether mitochondrial fission directly promotes diabetes‐induced cardiac dysfunction is still unknown. Melatonin exerts a substantial influence on the regulation of mitochon...

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Vydáno v:J Pineal Res
Hlavní autoři: Ding, Mingge, Feng, Na, Tang, Daishi, Feng, Jiahao, Li, Zeyang, Jia, Min, Liu, Zhenhua, Gu, Xiaoming, Wang, Yuemin, Fu, Feng, Pei, Jianming
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099285/
https://ncbi.nlm.nih.gov/pubmed/29575122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jpi.12491
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