RNA triphosphatase is essential in Schizosaccharomyces pombe and Candida albicans

BACKGROUND: The first two steps in the capping of cellular mRNAs are catalyzed by the enzymes RNA triphosphatase and RNA guanylyltransferase. Although structural and mechanistic differences between fungal and mammalian RNA triphosphatases recommend this enzyme as a potential antifungal target, it ha...

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Détails bibliographiques

Publié dans:	BMC Microbiol
Auteurs principaux:	Pei, Yi, Schwer, Beate, Saiz, Julia, Fisher, Robert P, Shuman, Stewart
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2001
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60989/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11737862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2180-1-29
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