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RNA triphosphatase is essential in Schizosaccharomyces pombe and Candida albicans

BACKGROUND: The first two steps in the capping of cellular mRNAs are catalyzed by the enzymes RNA triphosphatase and RNA guanylyltransferase. Although structural and mechanistic differences between fungal and mammalian RNA triphosphatases recommend this enzyme as a potential antifungal target, it ha...

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書目詳細資料
Main Authors: Pei, Yi, Schwer, Beate, Saiz, Julia, Fisher, Robert P, Shuman, Stewart
格式: Artigo
語言:Inglês
出版: BioMed Central 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC60989/
https://ncbi.nlm.nih.gov/pubmed/11737862
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