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Predictors of insufficient peak amikacin concentration in critically ill patients on extracorporeal membrane oxygenation
BACKGROUND: Amikacin infusion requires targeting a peak serum concentration (C(max)) 8–10 times the minimal inhibitory concentration, corresponding to a C(max) of 60–80 mg/L for the least susceptible bacteria to theoretically prevent therapeutic failure. Because drug pharmacokinetics on extracorpore...
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| 出版年: | Crit Care |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6098833/ https://ncbi.nlm.nih.gov/pubmed/30121083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-018-2122-x |
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