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Predictors of mosaic chromosome Y loss and associations with mortality in the UK Biobank

Mosaic loss of the Y chromosome (mLOY) is the most commonly reported large structural somatic event. Previous studies have indicated age and cigarette smoking increase the risk of mLOY, but the relationship of other exposures with mLOY and mLOY with disease has not been adequately investigated. We c...

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Vydáno v:Sci Rep
Hlavní autoři: Loftfield, Erikka, Zhou, Weiyin, Graubard, Barry I., Yeager, Meredith, Chanock, Stephen J., Freedman, Neal D., Machiela, Mitchell J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098142/
https://ncbi.nlm.nih.gov/pubmed/30120341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30759-1
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