Quantitative prediction of long-term molecular response in TKI-treated CML – Lessons from an imatinib versus dasatinib comparison

Longitudinal monitoring of BCR-ABL transcript levels in peripheral blood of CML patients treated with tyrosine kinase inhibitors (TKI) revealed a typical biphasic response. Although second generation TKIs like dasatinib proved more efficient in achieving molecular remission compared to first generat...

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Udgivet i:Sci Rep
Main Authors: Glauche, Ingmar, Kuhn, Matthias, Baldow, Christoph, Schulze, Philipp, Rothe, Tino, Liebscher, Hendrik, Roy, Amit, Wang, Xiaoning, Roeder, Ingo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098052/
https://ncbi.nlm.nih.gov/pubmed/30120281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29923-4
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