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Reduced tyrosine kinase inhibitor dose is predicted to be as effective as standard dose in chronic myeloid leukemia: a simulation study based on phase III trial data

Continuing tyrosine kinase inhibitor (TKI)-mediated targeting of the BCR-ABL1 oncoprotein is the standard therapy for chronic myeloid leukemia (CML) and allows for a sustained disease control in the majority of patients. While therapy cessation for patients appeared as a safe option for about half o...

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Опубликовано в: :Haematologica
Главные авторы: Fassoni, Artur C., Baldow, Christoph, Roeder, Ingo, Glauche, Ingmar
Формат: Artigo
Язык:Inglês
Опубликовано: Ferrata Storti Foundation 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278983/
https://ncbi.nlm.nih.gov/pubmed/29954936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.194522
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