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An intrinsic tumour eviction mechanism in Drosophila mediated by steroid hormone signalling

Polycomb group proteins are epigenetic regulators maintaining transcriptional memory during cellular proliferation. In Drosophila larvae, malfunction of Polyhomeotic (Ph), a member of the PRC1 silencing complex, results in neoplastic growth. Here, we report an intrinsic tumour suppression mechanism...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Jiang, Yanrui, Seimiya, Makiko, Schlumpf, Tommy Beat, Paro, Renato
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098038/
https://ncbi.nlm.nih.gov/pubmed/30120247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05794-1
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