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An intrinsic tumour eviction mechanism in Drosophila mediated by steroid hormone signalling
Polycomb group proteins are epigenetic regulators maintaining transcriptional memory during cellular proliferation. In Drosophila larvae, malfunction of Polyhomeotic (Ph), a member of the PRC1 silencing complex, results in neoplastic growth. Here, we report an intrinsic tumour suppression mechanism...
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| 發表在: | Nat Commun |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6098038/ https://ncbi.nlm.nih.gov/pubmed/30120247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05794-1 |
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