Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules

Tubulin polyglutamylation is a predominant axonemal post-translational modification. However, if and how axoneme polyglutamylation is essential for primary cilia and contribute to ciliopathies are unknown. Here, we report that Joubert syndrome protein ARL13B controls axoneme polyglutamylation, which...

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Bibliographic Details
Published in:Nat Commun
Main Authors: He, Kai, Ma, Xiaoyu, Xu, Tao, Li, Yan, Hodge, Allen, Zhang, Qing, Torline, Julia, Huang, Yan, Zhao, Jian, Ling, Kun, Hu, Jinghua
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098020/
https://ncbi.nlm.nih.gov/pubmed/30120249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05867-1
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