Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules

Tubulin polyglutamylation is a predominant axonemal post-translational modification. However, if and how axoneme polyglutamylation is essential for primary cilia and contribute to ciliopathies are unknown. Here, we report that Joubert syndrome protein ARL13B controls axoneme polyglutamylation, which...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: He, Kai, Ma, Xiaoyu, Xu, Tao, Li, Yan, Hodge, Allen, Zhang, Qing, Torline, Julia, Huang, Yan, Zhao, Jian, Ling, Kun, Hu, Jinghua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098020/
https://ncbi.nlm.nih.gov/pubmed/30120249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05867-1
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados