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Analogue Synthesis Reveals Decoupling of Antibiofilm and β-Lactam Potentiation Activities of a Lead 2-Aminoimidazole Adjuvant Against Mycobacterium smegmatis
Biofilm formation is one of the many mechanisms bacteria utilize to survive antibiotic treatment. It has been demonstrated that when Mycobacterium tuberculosis exists in a biofilm in vitro it expresses phenotypic resistance to antimicrobial drugs. Since the in vivo survival of M. tuberculosis follow...
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| Publicat a: | Chem Biol Drug Des |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6097888/ https://ncbi.nlm.nih.gov/pubmed/29663670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.13208 |
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