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An assay for de novo kinetochore assembly reveals a key role for the CENP-T pathway in budding yeast

Chromosome segregation depends on the kinetochore, the machine that establishes force-bearing attachments between DNA and spindle microtubules. Kinetochores are formed every cell cycle via a highly regulated process that requires coordinated assembly of multiple subcomplexes on specialized chromatin...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Lang, Jackie, Barber, Adrienne, Biggins, Sue
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097842/
https://ncbi.nlm.nih.gov/pubmed/30117803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37819
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