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Network-level allosteric effects are elucidated by detailing how ligand-binding events modulate utilization of catalytic potentials
Allosteric regulation has traditionally been described by mathematically-complex allosteric rate laws in the form of ratios of polynomials derived from the application of simplifying kinetic assumptions. Alternatively, an approach that explicitly describes all known ligand-binding events requires no...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6097697/ https://ncbi.nlm.nih.gov/pubmed/30086174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006356 |
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