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Influenza A virus-derived siRNAs increase in the absence of NS1 yet fail to inhibit virus replication

While the issue of whether RNA interference (RNAi) ever forms part of the antiviral innate immune response in mammalian somatic cells remains controversial, there is considerable evidence demonstrating that few, if any, viral small interfering RNAs (siRNAs) are produced in infected cells. Moreover,...

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Publicat a:RNA
Autors principals: Tsai, Kevin, Courtney, David G., Kennedy, Edward M., Cullen, Bryan R.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097656/
https://ncbi.nlm.nih.gov/pubmed/29903832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.066332.118
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