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Substituting Abacavir for Stavudine in Children Who Are Virally Suppressed Without Lipodystrophy: Randomized Clinical Trial in Johannesburg, South Africa

OBJECTIVES: Abacavir has replaced stavudine in antiretroviral therapy (ART) regimens because it has largely been phased out as a result of toxicity concerns; this loss has reduced further the already-limited drug options for children. Few data regarding virologic and metabolic outcomes among childre...

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Détails bibliographiques
Publié dans:J Pediatric Infect Dis Soc
Auteurs principaux: Strehlau, Renate, Shiau, Stephanie, Arpadi, Stephen, Patel, Faeezah, Pinillos, Francoise, Tsai, Wei-Yann, Coovadia, Ashraf, Abrams, Elaine, Kuhn, Louise
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097575/
https://ncbi.nlm.nih.gov/pubmed/29373687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jpids/pix110
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