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Characterization of mutations in PRNP (prion) gene and their possible roles in neurodegenerative diseases

Abnormal prion proteins are responsible for several fatal neurodegenerative diseases in humans and in animals, including Creutzfeldt–Jakob disease (CJD), Gerstmann–Sträussler–Scheinker disease, and fatal familial insomnia. Genetics is important in prion diseases, but in the most cases, cause of dise...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neuropsychiatr Dis Treat
Hauptverfasser: Bagyinszky, Eva, Giau, Vo Van, Youn, Young Chul, An, Seong Soo A, Kim, SangYun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097508/
https://ncbi.nlm.nih.gov/pubmed/30147320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S165445
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