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Adapted HCV JFH1 variant is capable of accommodating a large foreign gene insert and allows lower level HCV replication and viral production

Infectious HCV carrying reporter genes have further applications in understanding the HCV life cycle including replication, viral assembly and release. In this study, a full-length 3039bp LacZ gene was inserted into the derivative of JFH1-AM120 to develop an additional reporter virus. The results sh...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Wang, Qi, Hagedorn, Curt, Liu, Shuanghu
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097470/
https://ncbi.nlm.nih.gov/pubmed/30123070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.27411
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