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Synthesis and pre-clinical evaluation of a potential radiotracer for PET imaging of the dopamine D(3) receptor

There is considerable interest in using positron emission tomography (PET) imaging to understand the function of dopamine D(3) receptors. Due to high sequence homology with D(2) receptors, development of D(3)-selective PET radiotracers has been challenging. In an effort to overcome this issue, we re...

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Опубликовано в: :Medchemcomm
Главные авторы: Stewart, Megan N., Shao, Xia, Desmond, Timothy J., Forrest, Taylor J., Arteaga, Janna, Stauff, Jenelle, Scott, Peter J. H.
Формат: Artigo
Язык:Inglês
Опубликовано: Royal Society of Chemistry 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097203/
https://ncbi.nlm.nih.gov/pubmed/30151086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00094h
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