Inhibition of inflammation using diacerein markedly improved renal function in endotoxemic acute kidney injured mice

BACKGROUND: Inflammation is an important pathogenic component of endotoxemia-induced acute kidney injury (AKI), finally resulting in renal failure. Diacerein is an interleukin-1β (IL-1β) inhibitor used for osteoarthritis treatment by exerting anti-inflammatory effects. This study aims to investigate...

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Detalhes bibliográficos
Publicado no:Cell Mol Biol Lett
Main Authors: Yu, Guangzhe, Liu, Qian, Dong, Xuening, Tang, Kaihong, Li, Bohui, Liu, Chunmei, Zhang, Wenzheng, Wang, Yiduo, Jin, Yingyu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097202/
https://ncbi.nlm.nih.gov/pubmed/30140293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-018-0107-z
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