Lymphangiogenesis in kidney and lymph node mediates renal inflammation and fibrosis

Lymphangiogenesis is associated with chronic kidney disease (CKD) and occurs following kidney transplant. Here, we demonstrate that expanding lymphatic vessels (LVs) in kidneys and corresponding renal draining lymph nodes (RDLNs) play critical roles in promoting intrarenal inflammation and fibrosis...

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Vydáno v:Sci Adv
Hlavní autoři: Pei, Guangchang, Yao, Ying, Yang, Qian, Wang, Meng, Wang, Yuxi, Wu, Jianliang, Wang, Pengge, Li, Yueqiang, Zhu, Fengming, Yang, Juan, Zhang, Ying, Yang, Weiqi, Deng, Xuan, Zhao, Zhi, Zhu, Han, Ge, Shuwang, Han, Min, Zeng, Rui, Xu, Gang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594767/
https://ncbi.nlm.nih.gov/pubmed/31249871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw5075
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