Boosting Antitumor Drug Efficacy with Chemically Engineered Multidomain Proteins

A facile chemical approach integrating supramolecular chemistry, site‐selective protein chemistry, and molecular biology is described to engineer synthetic multidomain protein therapeutics that sensitize cancer cells selectively to significantly enhance antitumor efficacy of existing chemotherapeuti...

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Dades bibliogràfiques
Publicat a:Adv Sci (Weinh)
Autors principals: Kuan, Seah Ling, Fischer, Stephan, Hafner, Susanne, Wang, Tao, Syrovets, Tatiana, Liu, Weina, Tokura, Yu, Ng, David Yuen Wah, Riegger, Andreas, Förtsch, Christina, Jäger, Daniela, Barth, Thomas F. E., Simmet, Thomas, Barth, Holger, Weil, Tanja
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Full Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097141/
https://ncbi.nlm.nih.gov/pubmed/30128225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201701036
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