Boosting Antitumor Drug Efficacy with Chemically Engineered Multidomain Proteins

A facile chemical approach integrating supramolecular chemistry, site‐selective protein chemistry, and molecular biology is described to engineer synthetic multidomain protein therapeutics that sensitize cancer cells selectively to significantly enhance antitumor efficacy of existing chemotherapeuti...

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Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Kuan, Seah Ling, Fischer, Stephan, Hafner, Susanne, Wang, Tao, Syrovets, Tatiana, Liu, Weina, Tokura, Yu, Ng, David Yuen Wah, Riegger, Andreas, Förtsch, Christina, Jäger, Daniela, Barth, Thomas F. E., Simmet, Thomas, Barth, Holger, Weil, Tanja
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097141/
https://ncbi.nlm.nih.gov/pubmed/30128225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201701036
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