Marginal Effects of Systemic CCR5 Blockade with Maraviroc on Oral Simian Immunodeficiency Virus Transmission to Infant Macaques

Current approaches do not eliminate all human immunodeficiency virus type 1 (HIV-1) maternal-to-infant transmissions (MTIT); new prevention paradigms might help avert new infections. We administered maraviroc (MVC) to rhesus macaques (RMs) to block CCR5-mediated entry, followed by repeated oral expo...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Brocca-Cofano, Egidio, Xu, Cuiling, Wetzel, Katherine S., Cottrell, Mackenzie L., Policicchio, Benjamin B., Raehtz, Kevin D., Ma, Dongzhu, Dunsmore, Tammy, Haret-Richter, George S., Musaitif, Karam, Keele, Brandon F., Kashuba, Angela D., Collman, Ronald G., Pandrea, Ivona, Apetrei, Cristian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096825/
https://ncbi.nlm.nih.gov/pubmed/29925666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00576-18
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