Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population

AIMS/HYPOTHESIS: In a recent study using a standard additive genetic model, we identified a TBC1D4 loss-of-function variant with a large recessive impact on risk of type 2 diabetes in Greenlanders. The aim of the current study was to identify additional genetic variation underlying type 2 diabetes u...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Grarup, Niels, Moltke, Ida, Andersen, Mette K., Bjerregaard, Peter, Larsen, Christina V. L., Dahl-Petersen, Inger K., Jørsboe, Emil, Tiwari, Hemant K., Hopkins, Scarlett E., Wiener, Howard W., Boyer, Bert B., Linneberg, Allan, Pedersen, Oluf, Jørgensen, Marit E., Albrechtsen, Anders, Hansen, Torben
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096637/
https://ncbi.nlm.nih.gov/pubmed/29926116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-018-4659-2
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