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Downregulation of Dock1 and Elmo1 suppresses the migration and invasion of triple-negative breast cancer epithelial cells through the RhoA/Rac1 pathway

Dedicator of cytokinesis 1 (Dock1), a guanine nucleotide exchange factor, has been proven to facilitate cell survival, motility and proliferation via the activation of Ras-related C3 botulinum toxin substrate 1 (Rac1). Engulfment and cell motility 1 (Elmo1) serves as a mammalian homolog of Ced-12, w...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Liang, Yueyang, Wang, Shushu, Zhang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096110/
https://ncbi.nlm.nih.gov/pubmed/30127952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.9077
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