The polymorphism rs35767 at IGF1 locus is associated with serum urate levels

Previous studies suggested that the IGF-1/IGF-1 receptor signaling pathway may contribute to regulate uric acid levels. To confirm this hypothesis, we assessed the effects of the IGF-1-raising genetic variant rs35767 on urate levels in serum and urine, and we investigated IGF-1 ability to modulate t...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Mannino, Gaia C., Fuoco, Anastasia, Marini, Maria A., Spiga, Rosangela, Di Fatta, Concetta, Mancuso, Elettra, Perticone, Francesco, Andreozzi, Francesco, Sesti, Giorgio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095867/
https://ncbi.nlm.nih.gov/pubmed/30115944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29665-3
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