Pyruvate Kinase M2 Increases Angiogenesis, Neurogenesis, and Functional Recovery Mediated by Upregulation of STAT3 and Focal Adhesion Kinase Activities After Ischemic Stroke in Adult Mice

Ischemic stroke remains a serious threat to human life. Generation of neuronal and vascular cells is an endogenous regenerative mechanism in the adult brain, which may contribute to tissue repair after stroke. However, the regenerative activity is typically insufficient for significant therapeutic e...

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Vydáno v:Neurotherapeutics
Hlavní autoři: Chen, Dongdong, Wei, Ling, Liu, Zhi-Ren, Yang, Jenny J., Gu, Xiaohuan, Wei, Zheng Z., Liu, Li-Ping, Yu, Shan Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095793/
https://ncbi.nlm.nih.gov/pubmed/29869055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-018-0635-2
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