Pyruvate Kinase M2 Increases Angiogenesis, Neurogenesis, and Functional Recovery Mediated by Upregulation of STAT3 and Focal Adhesion Kinase Activities After Ischemic Stroke in Adult Mice

Ischemic stroke remains a serious threat to human life. Generation of neuronal and vascular cells is an endogenous regenerative mechanism in the adult brain, which may contribute to tissue repair after stroke. However, the regenerative activity is typically insufficient for significant therapeutic e...

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Publicado en:Neurotherapeutics
Autores principales: Chen, Dongdong, Wei, Ling, Liu, Zhi-Ren, Yang, Jenny J., Gu, Xiaohuan, Wei, Zheng Z., Liu, Li-Ping, Yu, Shan Ping
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2018
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095793/
https://ncbi.nlm.nih.gov/pubmed/29869055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-018-0635-2
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