Aberrant FGFR tyrosine kinase signaling enhances the Warburg effect by reprogramming LDH isoform expression and activity in prostate cancer

The acquisition of ectopic fibroblast growth factor receptor 1 (FGFR1) expression is well documented in prostate cancer (PCa) progression. How it contributes to PCa progression is not fully understood, although it is known to confer a growth advantage and promote cell survival. Here we report that F...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Liu, Junchen, Chen, Guo, Liu, Zezhen, Liu, Shaoyou, Cai, Zhiduan, You, Pan, Ke, Yuepeng, Lai, Li, Huang, Yun, Gao, Hongchang, Zhao, Liangcai, Pelicano, Helene, Huang, Peng, McKeehan, Wallace L., Wu, Chin-Lee, Wang, Cong, Zhong, Weide, Wang, Fen
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095720/
https://ncbi.nlm.nih.gov/pubmed/29891507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-3226
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