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Centromeric signaling proteins boost G1 cyclin degradation and modulate cell size in budding yeast
Cell size scales with ploidy in a great range of eukaryotes, but the underlying mechanisms remain unknown. Using various orthogonal single-cell approaches, we show that cell size increases linearly with centromere (CEN) copy number in budding yeast. This effect is due to a G1 delay mediated by incre...
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| 出版年: | PLoS Biol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6095599/ https://ncbi.nlm.nih.gov/pubmed/30080861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005388 |
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