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Spreading of Tau Pathology in Sporadic Alzheimer’s Disease Along Cortico-cortical Top-Down Connections

By using AT8-immunocytochemistry that visualizes hyperphosphorylated tau protein, we examined neurofibrillary changes related to sporadic Alzheimer’s disease (AD) in N = 40 individuals at neurofibrillary tangle (NFT) stages I–IV. We report the presence of abnormal tau changes within solitary pyramid...

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Bibliografiske detaljer
Udgivet i:Cereb Cortex
Main Authors: Braak, Heiko, Del Tredici, Kelly
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095209/
https://ncbi.nlm.nih.gov/pubmed/29982389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhy152
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