Matrix metalloproteinase 2/9-triggered-release micelles for inhaled drug delivery to treat lung cancer: preparation and in vitro/in vivo studies

BACKGROUND: Improvement in drug accumulation in the lungs through inhalation administration and high expression of MMP2 and MMP9 in lung tumors have both been widely reported. METHODS: MMP2/9-triggered-release micelles were constructed and in vitro and in vivo studies of inhalation administration ag...

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Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Wang, Xiaofei, Chen, Qinyue, Zhang, Xiaoyan, Ren, Xiaoqing, Zhang, Xiulei, Meng, Lin, Liang, Huihui, Sha, Xianyi, Fang, Xiaoling
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095127/
https://ncbi.nlm.nih.gov/pubmed/30147314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S166584
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