Matrix metalloproteinase 2/9-triggered-release micelles for inhaled drug delivery to treat lung cancer: preparation and in vitro/in vivo studies

BACKGROUND: Improvement in drug accumulation in the lungs through inhalation administration and high expression of MMP2 and MMP9 in lung tumors have both been widely reported. METHODS: MMP2/9-triggered-release micelles were constructed and in vitro and in vivo studies of inhalation administration ag...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Wang, Xiaofei, Chen, Qinyue, Zhang, Xiaoyan, Ren, Xiaoqing, Zhang, Xiulei, Meng, Lin, Liang, Huihui, Sha, Xianyi, Fang, Xiaoling
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095127/
https://ncbi.nlm.nih.gov/pubmed/30147314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S166584
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