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Design of a Small-Scale Multi-Inlet Vortex Mixer for Scalable Nanoparticle Production and Application to the Encapsulation of Biologics by Inverse Flash NanoPrecipitation

Flash NanoPrecipitation is a scalable approach to generate polymeric nanoparticles using rapid micromixing in specially designed geometries such as a confined impinging jets mixer or a Multi-Inlet Vortex Mixer (MIVM). A major limitation of formulation screening using the MIVM is that a single run re...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Markwalter, Chester E., Prud'homme, Robert K.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095068/
https://ncbi.nlm.nih.gov/pubmed/29772223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2018.05.003
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