SLC26A9 Gene Is Associated With Lung Function Response to Ivacaftor in Patients With Cystic Fibrosis

Ivacaftor is a drug used to treat cystic fibrosis (CF) patients carrying specific gating CFTR mutations. Interpatient variability in the lung response has been shown to be partly explained by rs7512462 in the Solute Carrier Family 26 Member 9 (SLC26A9) gene. In an independent and larger cohort, we a...

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Udgivet i:Front Pharmacol
Main Authors: Corvol, Harriet, Mésinèle, Julie, Douksieh, Isman-Hassan, Strug, Lisa J., Boëlle, Pierre-Yves, Guillot, Loïc
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095007/
https://ncbi.nlm.nih.gov/pubmed/30140228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00828
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