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Phosphoproteomic Alterations of Ionotropic Glutamate Receptors in the Hippocampus of the Ts65Dn Mouse Model of Down Syndrome

Down syndrome (DS), the main genetic cause of intellectual disability, is associated with an imbalance of excitatory/inhibitory neurotransmitter systems. The phenotypic assessment and pharmacotherapy interventions in DS murine models strongly pointed out glutamatergic neurotransmission alterations (...

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Veröffentlicht in:Front Mol Neurosci
Hauptverfasser: Gómez de Salazar, Macarena, Grau, Cristina, Ciruela, Francisco, Altafaj, Xavier
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095006/
https://ncbi.nlm.nih.gov/pubmed/30140203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00226
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