Accurate Titration of Infectious AAV Particles Requires Measurement of Biologically Active Vector Genomes and Suitable Controls

Although the clinical use of recombinant adeno-associated virus (rAAV) vectors is constantly increasing, the development of suitable quality control methods is still needed for accurate vector characterization. Among the quality criteria, the titration of infectious particles is critical to determin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Ther Methods Clin Dev
Egile Nagusiak: François, Achille, Bouzelha, Mohammed, Lecomte, Emilie, Broucque, Frédéric, Penaud-Budloo, Magalie, Adjali, Oumeya, Moullier, Philippe, Blouin, Véronique, Ayuso, Eduard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Gene & Cell Therapy 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090651/
https://ncbi.nlm.nih.gov/pubmed/30112419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.07.004
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