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Accurate Titration of Infectious AAV Particles Requires Measurement of Biologically Active Vector Genomes and Suitable Controls

Although the clinical use of recombinant adeno-associated virus (rAAV) vectors is constantly increasing, the development of suitable quality control methods is still needed for accurate vector characterization. Among the quality criteria, the titration of infectious particles is critical to determin...

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Podrobná bibliografie
Vydáno v:Mol Ther Methods Clin Dev
Hlavní autoři: François, Achille, Bouzelha, Mohammed, Lecomte, Emilie, Broucque, Frédéric, Penaud-Budloo, Magalie, Adjali, Oumeya, Moullier, Philippe, Blouin, Véronique, Ayuso, Eduard
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090651/
https://ncbi.nlm.nih.gov/pubmed/30112419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.07.004
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