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Real world evaluation of a novel lateral flow assay (AlphaKit® QuickScreen) for the detection of alpha-1-antitrypsin deficiency

BACKGROUND: Alpha-1-Antitrypsin (AAT) deficiency (AATD) is a hereditary disorder that manifests primarily as pulmonary emphysema and liver cirrhosis. The clinically most relevant mutation causing AATD is a single nucleotide polymorphism Glu342Lys (Z-mutation). Despite the recommendation to test ever...

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Publicado en:Respir Res
Main Authors: Greulich, Timm, Rodríguez-Frias, Francisco, Belmonte, Irene, Klemmer, Andreas, Vogelmeier, Claus F., Miravitlles, Marc
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090649/
https://ncbi.nlm.nih.gov/pubmed/30103740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0826-8
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